Created by Neuro-Immune Specialist, Dr. Kendal Stewart, Pregnenolone Plus is a custom formula that provides pregnenolone and the active precursor niacinamide for ultimate delivery of pregnenolone and aid in the protection of the mitochondrial. Pregnenolone is the key precursor pro-hormone involved in maintaining sufficient steroid hormone levels in the body. It is the precursor (building block) for other hormones in the body including cortisol, DHEA, estrogen, progesterone, testosterone and aldosterone.
Without pregnenolone there can be no human steroid hormone production.
Pregnenolone is known to modulate at least two key nerve receptors systems in the brain: NMDA receptors and GABA receptors. NMDA receptors are involved in learning, memory, and alertness. GABA receptors are involved in mood stability, relaxation, sex drive and sleep.
Niacinamide or otherwise known as Vitamin B3 works with vitamin B1, riboflavin (Vitamin B2), pyridoxine (vitamin B6), pantothenic acid, and biotin to break down and convert the carbohydrates, fats, and proteins in food into energy to help support the mitochondria. The involvement of niacin, an essential B vitamin, in cellular energy production makes it important for healthy cardiovascular function, nervous system function and immune function.
Improved Formula - Now with Organic Turmeric and Resveratrol!Palmitoylethanolamide (PEA) is a bio-identical fatty acid amide that Is normally synthesized by healthy tissue In the human body in response to inflammation. PEA is made by various plants and animals and is present throughout the animal kingdom. PEA can be found in many different tissuesincluding glia, neurons, retina, white blood cells, mast cells and adipocytes. Supplementing with PEA has been scientifically shown to naturally assist in the reduction of inflammation and to have neuro-protective and possibly pain control effects. This natural anti-inflammatory supports the nervous system and abnormal immune responses.*
Palmitoylethanolamide (PEA) – backed by more than 300+ medical studies, has been shown to be or assist with:
Mast cells are a type of immune system cell that responds to chemical signals from tissue injury. When mast cells “degranulate,” they release a payload of inflammatory cytokines, NGF, histamines, and other molecules in the surrounding tissue. These chemicals attract white blood cells and activate their immune response against pathogens. Mast cells also activate nociceptors (pain receptors) with the chemicals they secrete. How does it work?Palmitoylethanolamide is thought to act primarily on the Peroxisome Proliferator Activated Receptor Alpha (PPAR-α), a receptor in the cell nucleus. It also has affinity for the cannabinoid-like G-coupled receptors GPR55 and GPR119, although it has no affinity for the classical cannabinoid receptors CB1 and CB2. This is why it is sometimes referred to as a non-psychoactive “indirect endocannabinoid.”
NOTE: It does not block pain signals the way opioids and other analgesics do. Instead it works upstream by supporting the healthy function of glial cells and mast cells.*